TABLE 3.
Analysis of inhibition by ECTMWT-1 in the absence of ligand
The data are compared with a null hypothesis of 1 (no inhibition) using Student's t test. The wild-type and the A391E mutant show inhibition that is statistically significant, but only moderately.
| Receptor (no ligand) | N | Mean | S.D. | p value |
|---|---|---|---|---|
| WT | 6a | 0.67 | 0.23b | 0.02c |
| G380R | 6 | 1.24 | 0.34 | 0.14 |
| A391E | 5 | 0.60 | 0.25 | 0.02c |
a Shown are the number of independent data points measured in the absence of ligand.
b Shown is the standard deviation.
c Statistically significant (p < 0.05).