FIGURE 7.

The effect of adrenaline (adr, 1 μm) application on the rate of glucose load and clearance measured as dR/dt. A, the rate of glucose load obtained after the addition of extracellular glucose (5 mm) in fibroblasts (Fibro, black columns) and in adipocytes (Adipo, white columns) in basal (left panel) and insulin-stimulated (ins, 100 nm, right panel) conditions. B, the rate of glucose clearance obtained after superfusion with glucose-free extracellular solution in fibroblasts (black columns) and in adipocytes (white columns) in basal (left panel) and insulin-stimulated (100 nm, right panel) conditions. Numbers above columns indicate the number of cells tested; error bars show S.E. Asterisks indicate significant difference (*, p < 0.05; **, p < 0.01; ***, p < 0.001; two-way RM ANOVA).