TABLE 2.
Inward and outward slope conductance values for α1 and α1β Gly receptors expressed in HEK cells
Average values ± S.E. are in pS.
| Receptor type | Inward γ | na | Outward γ | na |
|---|---|---|---|---|
| α1 | 47.3 ± 2.1 | 3 | 65.3 ± 6.6 | 5 |
| α1K104E | 36.9 ± 0.6b | 5 | 19.8 ± 0.7c | 5 |
| α1β | 24.2 ± 1.4 | 5 | 33.2 ± 0.5 | 6 |
| α1K104Eβ | 22.5 ± 1.0 | 3 | 19.6 ± 1.5d | 4 |
| α1βK127E | 23.0 ± 3.3 | 4 | 30.5 ± 0.6 | 7 |
| α1K104EβK127E | 24.7 ± 1.5 | 6 | 10.7 ± 0.8d | 6 |
a n is the number of patches.
b p < 0.05 compared to wild-type conductance (one-way ANOVA followed by Dunnett's post-hoc test).
c p < 0.001 compared to wild-type conductance (one-way ANOVA followed by Dunnett's post-hoc test).
d p < 0.0001 compared to wild-type conductance (one-way ANOVA followed by Dunnett's post-hoc test).