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Differential contribution of AdipoR1 and AdipoR2 in mediating the effects of gAcrp and flAcrp on expression of M2 macrophage markers. RAW264.7 cells were transfected or not with either 100 nm AdipoR1, AdipoR2 siRNA, or scrambled siRNA and then cultured with or without 45 nm gAcrp or flAcrp for 18 h. Arg-1, Mgl2, and IL-4Rα mRNA were measured by qRT-PCR and normalized to 18 S mRNA. n = 4. + indicates p < 0.05 compared with nontransfected cells treated with gAcrp or flAcrp.
