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. 2003 Dec 5;100(26):15346–15351. doi: 10.1073/pnas.2536767100

Fig. 1.

Fig. 1.

Biosynthetic matrices in vitro. (A) Structure of TERP5 copolymer (x/y/z/m = 84.2:9.8:6:5 × 10–5, all in molar equivalents). (B) Corneal implant comprising collagen–TERP5 hydrogel, showing optical clarity that was not achieved in matrices containing only collagen (C). (Bar = 5 mm, thickness = 500 μm in both cases.) (D) Number of cell layers within the stratified epithelium grown on different hydrogels, n = 4 samples each. *, P < 0.05 by ANOVA. (E–G) Thickness of the epithelium grown on different hydrogels: collagen only (E), collagen–TERP (F), and collagen–TERP5 (G). (Bar = 30 μm for E–G.) (H) Nerve density within different hydrogels (collagen, a; collagen–TERP, b; collagen–TERP5, c) at 75 and 100 μm from the hydrogel edge, n = three samples each. *, P < 0.05 vs. collagen by ANOVA.