FIGURE 1.

PMA treatment and differential protein expression. A, cell morphology changes during cell differentiation induced by PMA. B, reproducibility of quantitative proteomics measurements. The abundance ratios in log₂ scale (log ratio) of proteins measured from the two biological replicates were compared in order to benchmark the quantification reproducibility. C, protein annotation by gene ontology cellular localization. D, a gradient distribution of the expression ratio (treated/untreated) for the quantified proteins.