Figure 4. Apoptosis of Ba/F3 cells induced by inhibition of BCR-ABL.
(A–B)Healthy Ba/F3 cell stained with MitoTracker Red and Annexin-Alexa 488. (C–F)Apoptotic cells stained with MitoTracker Red and Annexin-Alexa 488. Scale bar is 5 µm. (G) Histogram of cell death in Ba/F3 cells. From left to right, percent cell death of unperturbed (control), cells exposed to 5µM Dasatinib, and cells exposed to 5µM Dasatinib and 1 ng/ml IL-3. For each bar in the histogram, N=100 cells.
