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. Author manuscript; available in PMC: 2011 Dec 28.
Published in final edited form as: ACS Nano. 2010 Nov 30;4(12):7603–7611. doi: 10.1021/nn102345f

Figure 5. Apoptosis is induced in the majority of Ba/F3 cells with only eight molecules of the 23 kDa protein inhibitor of BCR-ABL.

Figure 5

Images of a (A)healthy and (B)dying cell observed using oblique illumination. Scale bar is 5 µm. (C) Histogram of cell death in Ba/F3 cells. From left to right, cells loaded with 100nm lipid nanocapsules containing AGT-PP1-1 for six hours and left unphotolyzed; cells in which 4 empty lipid nanocapsules were photolyzed; cells in which 1–2 lipid nanocapsules containing AGT-PP1-1 were photolyzed; cells in which 3–4 lipid nanocapsules containing AGT-PP1-1 were photolyzed; and cells in which 4 lipid nanocapsules containing AGT-PP1-1 were photolyzed in the presence of 1 ng/ml IL-3. For each bar in the histogram, N=25 cells.