Table 1.
Total (n = 144) | ||
---|---|---|
Median | Range | |
Age at testing (years) | 6.26 | 5.01 – 6.99 |
Age at LT (years) | 1.19 | 0.07 – 4.75 |
Interval from LT (years) | 4.87 | 2.03 – 6.68 |
PELD score at LT (9% missing) | 16.30 | −9.69 – 46.58 |
Height Z score at LT | −1.71 | −7.80 – 6.08 |
Weight Z score at LT | −1.28 | −8.94 – 2.19 |
INR at LT | 1.3 | 0.8 – 6.1 |
Albumin at LT (g/dL) | 3.1 | 1.5 – 4.8 |
Total Bilirubin at LT (mg/dL) | 11.1 | 0.0 – 58.0 |
Total Bilirubin at testing (mg/dL)** | 0.5 | 0.1 – 5.6 |
Albumin at testing (g/dL)** | 4.2 | 2.8 – 5.1 |
N | % | |
Female | 83 | 58% |
Race | ||
White | 84 | 58% |
Black | 21 | 15% |
Hispanic | 21 | 15% |
Other or missing (n=1) | 18 | 12% |
Primary Diagnosis | ||
Biliary Atresia | 84 | 58% |
Acute Liver Failure | 14 | 10% |
Other cholestatic | 20 | 14% |
Metabolic* | 14 | 10% |
Other | 12 | 8% |
Status at transplant | ||
ICU | 30 | 21% |
Hospitalized | 21 | 15% |
Home | 93 | 65% |
Number of Liver transplants | ||
1 | 137 | 95% |
2 | 6 | 4% |
3 | 1 | 1% |
Initial immunotherapy*** | ||
Cyclosporine | 31 | 22% |
Tacrolimus | 94 | 65% |
Induction therapy | ||
None | 100 | 69% |
Yes | 44 | 31% |
Total number of rejection episodes | ||
0 | 60 | 42% |
1 | 52 | 36% |
2 – 7 | 32 | 22% |
Metabolic diagnosis included Urea cycle defects (n=2), Wilson’s disease (n=0), alpha-1-anti-trypsin deficiency (n=3), Tyrosinemia (n=2), Neonatal Hemachromatosis (n=1), Inborn error in bile acid metabolism (n=1), other metabolic (n=5)
Values missing on 5% of cohort
Values missing on 13% of cohort