| Extensions to existing pathways (enzymatic) |
IspG and IspH; two additional enzymes in the nonmevalonate isoprenoid biosynthesis pathway. Known, but not yet in EcoCyc |
YqiA; an α—β hydrolase predicted to be associated to ubiquinone metabolism |
| Extensions to existing pathways (nonenzymatic) |
NarU and NarK; two nitrate/nitrite transporters linked with the nitrate reductase complex |
YbaD; a transcription factor possibly regulating riboflavin biosynthesis enzymes |
| Functional links between pathways |
A predicted link between the metabolism of selenocysteine, and formate dehydrogenase; the latter is known to contain selenocysteine |
A predicted link between coenzyme A biosynthesis and the metabolism of nucleotides. Supported by multiple observations |
|
A functional link between nonmevalonate isoprenoid biosynthesis and the subsequent biosynthesis of polyisoprenoids |
A predicted link between phospholipid biosynthesis and thiamine biosynthesis: conserved neighborhood between pgpA and thiL
|
| Entirely novel functional systems/pathways |
A large, conserved module consisting of enzymes needed to use ethanolamine as a carbon/nitrogen source. Not yet annotated in EcoCyc |
An uncharacterized, conserved functional module, containing the domains integrin I and AAA—ATPase. This combination of domains is known to occur in metal chelatases. |
