. Author manuscript; available in PMC: 2011 Dec 22.

Published in final edited form as: J Am Chem Soc. 2010 Nov 29;132(50):17933–17944. doi: 10.1021/ja1086485

Table 1.

Nucleophilic additions to 4,5-indolyne 29

entry	trapping agent	yield (ratio)
1^a		80% yield (3:1)
2^a		91% yield (12.5:1)
3^a		88% yield (2:1)
4^b		58% yield (10:1)
5^a	KCN	85% yield (3.3:1)

Conditions: 27, CsF, CH₃CN, 50 °C.

Conditions: 27, CsF, CH₃CN, 40 °C.