Table 9.
| |||
---|---|---|---|
trapping agent (Nuc) | N-substitudent (R) | yield | ratio (C6 : C7) |
Me | 53% | C6 only | |
H | 52% | 10.7 : 1 | |
Boc | 59% | C6 only | |
Me | 91% | C6 only | |
H | 79% | 13.8 : 1 | |
Boc | 66% | C6 only | |
Bn–N3 | Me | 77% | C6 only |
H | 60% | 6.9 : 1 | |
Boc | 63% | C6 only | |
KCN | Me | 70% | C6 only |
H | 44% | 7.6 : 1 | |
Boc | 80% | C6 only |
Conditions: see supporting information.