Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison between MES seizure protection effect of NLCs of VPA (4 mg/kg) in nasal route and sodium valproate solution (150 mg/kg) as positive control in IP route after different times of drug administration (P > 0.05) (n = 6). There is no statistical difference in any times according to independent t test.
Abbreviations: E:F ratio, extension:flexion ratio; VPA, valproic acid; NLCs, nanostructured lipid carriers; MES, maximal electroshock; IP, intraperitoneal.
