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. 2011 Feb 20;6:397–405. doi: 10.2147/IJN.S16144

Figure 2.

Figure 2

A) Determination of folate content conjugated with human serum albumin, a) N-hydroxysuccinimide ester of folate, b) tryptic hydrolysis of folate-conjugated human serum albumin nanoparticles, c) tryptic hydrolysis of human serum albumin nanoparticles; the particle size distribution of B) micronized 10-hydroxycamptothecin, C) micronized 10-hydroxycamptothecin-loaded folate-conjugated human serum albumin nanoparticles, D) HSA-nHCPT-NPs; the morphology observation of E) raw hydroxycamptothecin, F) micronized hydroxycamptothecin, G) micronized 10-hydroxycamptothecin-loaded folate-conjugated human serum albumin nanoparticles, and H) human serum albumin-loaded 10-hydroxycamptothecin nanoparticles, by scanning electron microscopy.