Table 4.
Neurocognition as a predictor of response to cognitive rehabilitation (n=3).
| Study | Sample | Intervention | Intervention Duration | Neurocognitive Measures | Outcome Measures | Finding | Effect Sizes |
|---|---|---|---|---|---|---|---|
| Fiszdon, Cardenas, Bryson & Bell, 2005 | 58 outpatients MA=41.4 % male=76 Edu=13.2 Dur ill=? AO=? Hosp=? |
Comprehensive, computer- assisted drill- and-practice approach to cognitive remediation. | 6-months | Digit span, CPT, TMT B, WCST, HVLT, Full-scale IQ | Proximal Measure: Digits sequenced recall test | Vigilance, immediate verbal memory, latency between last training and testing, and hostility combined to account for 70% of improvement in remediation trial. | NR |
| Kurtz, Wexler, Fujimoto, Shagan & Seltzer, 2008 | 36 outpatient MA=32.4 % male=69 Edu=13.4 Dur ill=8.7 AO=24.2 Hosp=3.9 |
Comprehensive, computer- assisted drill- and-practice approach to cognitive remediation. | 12-months | Vocabulary, Digit Span, CVLT, PCET | Mediational Measure: UPSA | Sustained auditory attention explained variance in improved everyday life skills beyond that predicted by demographic, symptom and process variables. | For total UPSA scores: 50% moderate-to-large, 25% small-to-moderate, 25% minimal to none. |
| Medalia & Richardson, 2005 | Three samples: 55,36 and 26 MA=36, 35, 36 % ‘male=62, 67, 62 Edu=11, 10, ? Dur ill=? AO=? Hosp=? |
NEAR | 10–26 sessions | RBANS, WAIS, Minnesota Clerical Test, CVLT | Proximal Measures: RBANS, WAIS, Minnesota Clerical Test, CVLT | Minnesota Clerical Test at baseline predicted a stronger response to cognitive remediation. Other baseline measures did not predict response to the cognitive remediation intervention. | NR |
Note: AO=Age-of-onset; CPT=Continuous Performance Test; CVLT=California Verbal Learning Test; Dur ill=Duration of illness; Edu=Education; HVLT=Hopkins Verbal Learning Test; MA=Mean Age; NEAR=Neuropsychological Education to Rehabilitation NR: Not reported; PCET=Penn Conditional Exclusion Test; RBANS=Repeatable Battery for the Assessment of Neuropsychological Status; TMT-B=Trailmaking Test B; WAIS=Wechsler Adult Intelligence Scale; WCST=Wisconsin Card Sorting Test.