Figure 8.

The fraction of unfolded species populated at equilibrium for each variant, $\text{mAS}-\text{SOD}{1}_{\text{Zn}}^{\text{SS}}$ (black), $\text{mAS}-\text{SOD}{1}_{\text{Apo}}^{\text{SS}}$ (light gray), $\text{mAS}-\text{SOD}{1}_{\text{Apo}}^{2\text{SH}}$ (dark gray) at 10 μM protein concentration, 20 °C and pH 7.2. The errors for A4V, L38V, G93A and L106V $\text{mAS}-\text{SOD}{1}_{\text{Apo}}^{2\text{SH}}$ were approximated at 20%. All other errors were determined from the error in the ΔG°.