Table 2.
Bivariate and Multivariable Associations of Potential Predictors of Overall Failure versus Overall Success, Controlling Treatment Group and Site
| Predictor | Univariable Analyses |
Final Multivariable Analysis* |
||
|---|---|---|---|---|
| p-value | Adjusted Odds Ratio (95%CI) | p-value | Adjusted Odds Ratio (95%CI) | |
| Treatment Group | 0.25 | 0.44 | ||
| RMUS | Reference | Reference | ||
| TMUS | 1.22(0.87–1.70) | 1.15(0.81–1.63) | ||
| Race | 0.53 | |||
| Hispanic | Reference | |||
| Non-hispanic White | 1.56 ( 0.85–2.85) | |||
| Non-hispanic Black | 1.54 ( 0.50–4.70) | |||
| Non-hispanic Other | 1.27 ( 0.52–3.12) | |||
| Marital Status | 0.15 | |||
| Not married | Reference | |||
| Married/Living as married | 0.76 ( 0.53–1.10) | |||
| Education | 0.44 | |||
| <HS | Reference | |||
| HS/GED | 1.56 ( 0.67–3.64) | |||
| >HS | 1.78 ( 0.78–4.05) | |||
| BA/BS/Grad/Prof | 1.75 ( 0.76–4.03) | |||
| Smoking | 0.79 | |||
| Never smoked | Reference | |||
| Former smoker | 0.93 ( 0.64–1.35) | |||
| Current smoker | 1.12 ( 0.67–1.87) | |||
| HRT Use | 0.11 | |||
| No | Reference | |||
| Yes | 0.87 ( 0.57–1.34) | |||
| Pre-Menopausal | 0.64 ( 0.42–0.98) | |||
| Previous Prolapse Surgery, yes | 0.12 | 1.99 ( 0.83–4.75) | ||
| Prolapse Stage | 0.60 | |||
| Stage 0–1 | Reference | |||
| Stage 2 | 1.18 ( 0.83–1.70) | |||
| Stage 3+ | 0.96 ( 0.50–1.87) | |||
| Prior UI Surgery, yes | 0.0002 | 2.69 ( 1.59–4.55) | 0.01 | 1.99(1.14–3.47) |
| Fecal Incontinence Symptoms, yes | 0.61 | 1.11 ( 0.75–1.64) | ||
| Concomitant Surgery, yes | 0.32 | 0.81 (0.54–1.22) | ||
| Vaginal Deliveries | 0.19 | |||
| Never delivered | Reference | |||
| One delivery | 1.11 ( 0.59–2.11) | |||
| Two deliveries | 0.68 ( 0.38–1.22) | |||
| Three deliveries | 1.13 ( 0.62–2.06) | |||
| Four or more deliveries | 1.00 ( 0.51–1.94) | |||
| PVR at Discharge, yes >100 | 0.21 | 0.77 ( 0.51–1.16) | ||
| Number of Comorbidities | 0.20 | |||
| 0 | Reference | |||
| 1 | 1.52 ( 0.95–2.42) | |||
| 2+ | 1.22 ( 0.69–2.15) | |||
| Qtip Delta<30, yes | 0.001 | 1.95 (1.32–2.89) | ||
| Qtip Max Straining<30, yes | 0.005 | 1.97 (1.23–3.14) | 0.01 | 1.89(1.16–3.05) |
| Empty Bladder Stress Test | 0.22 | |||
| Positive | 1.24 (0.88–1.74) | |||
| Negative | Reference | |||
| Age (10 per unit), years | 0.02 | 1.21 ( 1.03–1.42) | ||
| BMI | 0.005 | 1.04 ( 1.01–1.07) | ||
| EBL During Sling (10 per unit), ml | 0.84 | 1.00 ( 0.96–1.04) | ||
| Brink Score | 0.045 | 0.91 ( 0.84–1.00) | ||
| UDI Total (10 per unit) | 0.004 | 1.06 ( 1.02–1.10) | ||
| IIQ Total (10 per unit) | 0.006 | 1.03 ( 1.01–1.04) | ||
| Stress Score(10 per unit) | 0.002 | 1.85 ( 1.26–2.70) | ||
| Urge Score(10 per unit) | <.0001 | 2.88 ( 1.83–4.55) | 0.007 | 1.97(1.21–3.21) |
| Leaks/day | 0.0005 | 1.12 ( 1.05–1.19) | ||
| Pad Weight (10 per grams) | <.0001 | 1.07 ( 1.04–1.11) | 0.003 | 1.06(1.02–1.10) |
*
Hosmer and Lemeshow Goodness-of-Fit Test p-value=0.70
RMUS-retropubic midurethral sling; TMUS-transobturator midurethral sling; HS-high school; GED-graduate equivalency degree; BA/BS-bachelors degree; Grad-post-graduate degree; Prof-professional degreel HRT-hormone replacement therapy; UI-urinary incontinence; PVR-postvoid residual; BMI-body mass index; EBL-estimated blood loss; ml-milliliter; UDI-Urogenital Distress Inventory; IIQ-Incontinence Impact Questionnaire.