Fig. 4.
The amount and rate of thrombin generation with endogenous microparticle-derived PPL is increased in male VTE cases. The trigger is 5 pM tissue factor without added PPL and the non-sedimentable activity has been subtracted, as described for Fig. 3. a) Box and whisker plots showing the peak height for VTE control or case plasmas, symbols as described in Fig. 1a. b) Rate of thrombin generation, calculated by dividing the peak height by the time to reach the peak. Single asterisk (*) indicates p-value (Mann-Whitney-Wilcoxon rank sum) of 0.007.