Fig. 6.

Annexin V/CD42-positive MP neither increases with age nor correlates to procoagulant phospholipid measured by thrombin generation. Microparticle analysis using flow cytometry was performed on isolated and washed microparticles that were co-stained for both annexin V and CD42. Thrombin generation analysis was performed in parallel on citrated platelet poor plasma processed at the same time. a) AnnexinV/CD42-double positive microparticle versus age. Control and case samples data are plotted with symbol colors defined in Fig. 6. b) The number of annexin V/CD42-positive microparticles per µL versus peak thrombin. Control and case samples data are plotted with symbols defined in Fig. 6a.