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. Author manuscript; available in PMC: 2011 Nov 1.
Published in final edited form as: J Immunol. 2010 Oct 4;185(9):5453–5462. doi: 10.4049/jimmunol.1001153

FIGURE 4.

FIGURE 4

Impaired production of IL-17A, IL-17F, and IL-22 in IL-23–deficient mice. IL-17A, IL-17F, IL-22, IL-21, IFN-γ, and TNF-α mRNA expression 48 h after C. albicans skin infection in WT and the various knockout mice as measured by qPCR. Each symbol indicates the amount of mRNA transcript as measured by arbitrary units (AU) of a single specimen, and horizontal bars denote the mean of scatterplots. Data were analyzed using Kruskal–Wallis test and Scheffe's F test. IL-17A: *p < 0.001 versus WT. IL-17F: *p < 0.001 versus WT. IL-22: *p < 0.001 versus WT. IFN-γ: *p < 0.01 for IL-23p19−/− and IL-12p35−/− versus WT; *p < 0.01 for IL-12/23p40−/− versus WT. TNF-α: *p < 0.01 versus WT.