FIGURE 7.
Higher numbers of CD3+ T cells in WT mouse skin compared with that in IL-17A−/− and IL-22−/− mice. A, H&E, CD3, F4/80, and Gr-1 staining of skin 4 d postinfection with C. albicans showing a large collection of fungal elements in the deep dermis and superficial fat. H&E and Gr-1 staining, original magnification ×10; scale bars, 0.2 mm. CD3 and F4/80 staining, original magnification ×40; scale bars, 0.025 mm. B, Quantification of CD3+ and F4/80+ cells and grading of Gr-1 staining in each of the four groups of mice shown in A. Data are expressed as mean ± SD. Bar graphs were analyzed with Kruskal–Wallis test and Scheffe's F test. *p < 0.025; **p, 0.001 versus WT.