Fig. 4.
Colocalization to intracellular vesicles is specific for proteins that interact with CD63. (A) COS cells were transfected with AQP4 alone or were cotransfected with AQP4 and CD63-FL (AQP4 + CD63-FL). The cells were lysed in 1% Triton X-100 and immunoprecipitated with anti-FLAG mAb. The immunoprecipitated material and the cell lysates were probed with anti-AQP4 pAb. (B) COS cells were transfected with either AQP4 (green) or AQP4 and CD63-FL (red). AQP4 was detected with anti-AQP4 pAb, and CD63 was detected with anti-FLAG mAb. (Scale bar is 10 μm.)
