Table 2. Associations of reported CHD SNPs with CHD risk.

SNP	Chromosome	Genes	Call rate%	Alleles Risk/Reference	Risk allele frequency*		Odds Ratio (95% CI)	P value┼	PAR %
					Hispanics	Caucasians
rs646776	1p13.3	CELSR2-PSRC1-SORT1	0.988	A/G	0.78	0.75	1.15 (1.03-1.29)	0.02	10.5
rs599839	1p13.3	CELSR2-PSRC1-SORT1	0.979	A/G	0.76	0.72	1.11 (0.99-1.24)	0.07	7.7
rs501120	10q11.21	CXCL12	0.979	A/G	0.81	0.83	1.22 (1.08-1.38)	0.00	15.2
rs1746048	10q11	CXCL12	0.982	C/T	0.81	0.85	1.21 (1.07-1.37)	0.00	14.6
rs2259816	12q24.31	HNF1A,C12orf43	0.987	A/C	0.38	0.38	1.02 (0.92-1.12)	0.73	0.8
rs9818870	3q22.3	MRAS	0.988	T/C	0.09	0.17	1.00 (0.85-1.18)	0.98	0.0
rs2048327	6q26–q27	SLC22A3	0.988	G/A	0.42	0.35	1.00 (0.91-1.10)	0.93	0.0
rs3127599	6q26–q27	LPAL2	0.984	A/G	0.20	0.33	0.97 (0.86-1.09)	0.59	0.6
rs7767084	6q26–q27	LPA	0.985	C/T	0.17	0.16	1.02 (0.90-1.15)	0.80	0.3
rs10755578	6q26–q27	LPA	0.986	G/C	0.37	0.50	0.96 (0.87-1.06)	0.45	1.5
rs10757274	9p21.3	CDKN2A,CDKN2B	0.987	G/A	0.46	0.50	1.16 (1.05-1.28)	0.00	6.8
rs4977574	9p21.3	CDKN2A,CDKN2B	0.987	G/A	0.45	0.46	1.16 (1.05-1.27)	0.00	6.8
rs2383206	9p21.3	CDKN2A,CDKN2B	0.984	G/A	0.59	0.53	1.14 (1.03-1.26)	0.01	7.6
rs1333049	9p21.3	CDKN2A,CDKN2B	0.988	C/G	0.50	0.46	1.12 (1.02-1.24)	0.02	5.7

The risk alleles are highlighted in bold; EAF, effect allele frequency; PAR, population attributable risk

^┼P values were two-sided from the 1 df test for trend from unconditional logistic regression model

^*risk allele frequency in the study samples of hispanics; and in the CEU samples from HapMap