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β-APP is predominantly localized to proximal but not distal or SCWM YFP+ swellings. A–C, Representative image of an axotomized YFP+ neuron (A) labeled with APP (B). The percentage of proximal YFP+ swellings (white/black arrows) exhibiting APP immunoreactivity is significantly greater (C) than the percentage of distal (white/black arrowheads) and SCWM (red arrowheads) YFP+ swellings that are immunopositive for APP. +p < 0.001; *p < 0.01. Scale bar: (in B) A, B, 40 μm.
