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. Author manuscript; available in PMC: 2011 Apr 13.
Published in final edited form as: Sci Transl Med. 2011 Jan 19;3(66):66ra5. doi: 10.1126/scitranslmed.3001542

Fig. 7.

Fig. 7

A549 cells cultured in media conditioned by intact ECs, but not perlecan-silenced ECs, were less metastatic than control cells. (A) Increase in lung weights, relative to tumor-free animals, of A549 cells cultured for 4 days in unconditioned (control) media, media conditioned by intact ECs, and media conditioned by perlecan-silenced ECs (ECshPerl). (B) Metastatic index (see Materials and Methods) of lung cryosections in the above groups. *P < 0.05 versus control group by t test. Error bars show SEM.