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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Cancer Res. 2011 Mar 1;71(5):1584–1596. doi: 10.1158/0008-5472.CAN-10-3166

Figure 2.

Figure 2

Gross phenotypic changes in the reproductive tracts of APCflox/flox, APCcko female mice. (Panel A) 4wk old uteri from representative APCflox/flox and APCcko mice are shown. White arrows point to the oviducts of control and mutant mice, which are shorter and exhibit less coiling in mutants. (Panel B) The average uterine wet weight of 4-week-old APCcko/ mice was also significantly smaller (p < 0.05) when compared with controls (0.75 g ± 0.76 vs. 1.34 g ± 0.11, respectively). (Panel C) Grossly enlarged APCcko uteri with blood filled cyst (black arrow) (D) Splenomegaly in APCcko mice compared to controls. o: ovary; M: mutant; C: control; S: spleen.