Table 4. Newborn and adult body weights.
Newborn body weights from GT1AS × GT1AS matings
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Adult body weights† (percent of NT same-sex sibling weights)
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Liveborn NT pups, g | Liveborn GT1AS pups, g | Stillborn GT1AS pups, g | NT Males | GT1AS Males (heterozygotes) | NT Females | GT1AS Females (heterozygotes) |
1.60 ± 0.05 (n = 21) | 1.54 ± 0.05 (n = 24) | 1.04 ± 0.07* (n = 4) | 100 ± 1% (n = 7) | 103 ± 2% (n = 3) | 100 ± 2% (n = 11) | 99 ± 3% (n = 10) |
All GT1AS adults were heterozygous (homozygotes nonviable). n = No. of mice examined. *, P < 0.001 vs. both liveborn NT pups and liveborn GT1AS pups.
Mice surviving to adulthood were taken from randomly selected litters and weighed at 2-5 months of age. Therefore, the adult weights are expressed as percent of NT same-sex sibling controls for comparison.