TABLE 3.
Purification of NrdF from E. coli GR536a
Purification step | Protein (mg) | Total activity (nmol/min) | Specific activity (nmol/min/mg) | Percent recovery | Purification factor |
---|---|---|---|---|---|
Crude extractb | 7100 | 5400 | 0.76 | 100 | 1 |
(NH4)2SO4 / G25b | 5400 | 2100 | 0.39 | 40 | 0.5 |
Ni-NTA | 140 | 1200 | 8.8 | 22 | 12 |
DEAE | 7.1 | 400 | 56 | 7 | 74 |
FPLC 1 | 0.39 | 230 | 580 | 4 | 780 |
FPLC 2 | 0.15 | 110 | 720 | 2 | 950 |
NrdF was purified from 88 g of cells
The results shown for these steps represent the aggregate of 3 separate purifications from ~30 g cells