Table 3.
Enzyme activities and glycogen concentration in different muscle groups in carriers and non-carriers of the PRKAG3 mutation.
| m. longissimus dorsi | m. semitendinosus | m. biceps femoris | ||||
|---|---|---|---|---|---|---|
| Carriers (n = 6) | Non-carriers (n = 6) | Carriers (n = 6) | Non-carriers (n = 7) | Carriers (n = 7) | Non-carriers (n = 7) | |
| CS | 20 ± 3 * | 8 ± 5 | 15 ± 1 | 13 ± 2 | 19 ± 2 | 20 ± 1 |
| HAD | 24 ± 1 | 24 ± 2 | 26 ± 2 | 26 ± 2 | 31 ± 3 | 29 ± 3 |
| HK | 8 ± 1 * | 3 ± 2 | 7 ± 1 * | 4 ± 1 | 8 ± 1 * | 5 ± 1 |
| Phosphorylase | 18 ± 2 * | 15 ± 2 | 17 ± 2 | 15 ± 3 | 16 ± 2 * | 11 ± 1 |
| LDH | 2778 ± 328 * | 3199 ±134 | 2929 ± 187 * | 3255 ± 203 | 2474 ± 219 | 2561 ± 179 |
| Glycogen | 725 ± 46 * | 458 ± 32 | 600 ± 49 * | 349 ± 18 | 681 ± 42 * | 420 ± 28 |
Data are expressed as mmol/kg/min for citrate synthase (CS), 3-hydroxyacyl-CoA (HAD), hexokinase (HK), phosphorylase, lactate dehydrogenase (LDH) and in mmol/kg for glycogen concentration.
Data as means ± SE. * P < 0.05 significantly different from non-carriers.