Table 2.

Genotype and allele frequencies of the C1772T and the G1790A polymorphisms of the HIF1A gene in PE patients and the control group

Nucleotide	Amino acids	Genotypes	PE (%)	Control (%)	P-value	OR (95% CI)
C1772T	Pro582	CC	137 (91.3)	95 (90.5)
	Ser582	CT	13 (8.7)	10 (9.5)
		TT	0 (0.0)	0 (0.0)
		CT + TT	13 (8.7)	10 (9.5)	0.203 *	0.485 (0.178-1.067)
		Allele
		C	287 (95.7)	200 (95.2)	0.831	0.906 (0.389-2.107)
		T	13 (4.3)	10 (4.8)
		Genotypes
G1790A	Ala588	GG	150 (100.0)	104 (99.3)
	Thr588	GA	0 (0.0)	1 (0.7)
		AA	0 (0.0)	0 (0.0)
		GA + AA	0 (0.0)	1 (0.7)	0.412 **	0.232 (0.009-5.737)
		Allele
		G	300 (100.0)	209 (99.5)	0.411	0.232 (0.009-5.737)
		A	0 (0.0)	1 (0.5)

PE, preeclampsia; OR, odds ratio; CI, confidence intervals. * Calculations were performed CC vs. CT + TT. ** Calculations were performed GG vs. GA + AA