Table V.

Neural Responses to Reward-Based Learning: MNI Anatomical Coordinates for Instructive Feedback (Deterministic Positive Rewards as Compared to Rest) for Monetary and Social Runs by Group

Anatomical region		Monetary positive deterministic rewards>rest										Social positive deterministic rewards>rest
		TD					ASD					TD					ASD					TD>ASD
		BA	x	y	z	Z	BA	x	y	z	Z	BA	x	y	z	Z	BA	x	y	z	Z	BA	x	y	z	Z
Caudate	L												−8	16	0	2.52							−14	18	6	2.97
	R												8	18	0	2.53							16	4	12	2.75
Putamen	L																						−26	14	0	2.60
	R		32	−16	2	3.67																	20	10	−2	2.29
Nucleus accumbens	L		−8	10	−8	2.23
	R
Orbitofrontal	L	47	−24	10	−18	3.19
	R	47	38	24	−18	3.18
Inferior frontal gyrus	L
	R						45	52	26	14	2.91
Middle frontal gyrus	L						9	−42	16	36	3.13
	R
Precentral gyrus	L						4	−44	8	34	3.03
	R	4	34	−24	42	3.06	4	48	2	30	3.48
Frontal Pole	L											10	−16	66	20	2.29
	R						10/11	44	50	2	3.33											10	30	50	−6	3.32
Hippocampus/Parahippocampal gyrus	L
	R	35	24	−6	−26	2.35		30	−20	−14	2.44
Cingulate
Anterior												24	−2	38	6	3.39						24	−4	36	12	3.23
Paracingulate		32	6	44	24	3.09
Posterior		31	2	−22	46	3.08
Subcallosal	L
	R											32	−2	24	−12	2.41
Insula	L
	R
Fusiform gyrus	L	37	−20	−74	−10	4.03	37	−38	−68	−18	3.94	37	−42	−50	−20	3.46	37	−32	−76	−12	3.99		−26	18	−10	3.45
	R	37	34	−68	−14	4.16	37	26	−70	−16	3.84	37	42	−52	−18	3.61	37	20	−12	−12	3.74
Occipital cortex	L	17	2	−92	6	4.18											18	−22	−96	−8	3.59
	R							34	−66	46	3.68						18	8	−94	16	3.57
Inferior parietal lobule	L						7	−46	−52	50	3.44
	R
Supramarginal gyrus	L						40	−44	−52	50	3.09
	R						40	50	−46	50	2.91

BA refers to putative Brodmann’s Area; L and R refer to left and right hemispheres; x, y, and z refer to the left–right, anterior–posterior, and inferior–superior dimensions, respectively; Z refers to the Z-score at those coordinates (local maxima or submaxima). Cluster corrected for multiple comparisons, Z>1.96, P<0.05.