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. 2003 Dec 5;100(26):15712–15717. doi: 10.1073/pnas.2536828100

Fig. 5.

Fig. 5.

HFD leads to expedited lipodystrophy and severe IR in FKOγ mice. (A and B) Body weight gain and fat pad mass change of HFD-fed Con and FKOγ mice. Values are the mean ± SEM (n = 10). *, P < 0.05. (C) Histology of BAT (Upper) and WAT (Lower) from Con and FKOγ mice. Fasting blood glucose (D) and insulin (E) levels in HFD-fed animals are shown. HFD causes similar elevation of fasting blood glucose levels but higher levels of insulin in FKOγ mice. Values are the mean ± SEM (n = 10). *, P < 0.05, FKOγ vs. Con. (F) Insulin tolerance test after HFD feeding. Values are the mean ± SEM (n = 10). *, P < 0.05, FKOγ vs. Con.