Table 1. Metabolic parameters of 14-month-old FKOγ mice.
| Genotype | Con | FKOγ |
|---|---|---|
| Blood glucose, mg/dl | ||
| Basal | 137 ± 5.6 | 125 ± 5.4 |
| Clamp | 148 ± 1.9 | 148 ± 0.96 |
| Blood insulin, ng/ml | ||
| Basal | 0.87 ± 0.02 | 0.82 ± 0.25 |
| Clamp | 9.4 ± 0.6 | 10.3 ± 0.6 |
| FFA (mmol/l) | ||
| Basal | 0.82 ± 0.09 | 0.99 ± 0.05 |
| Clamp | 0.43 ± 0.02* | 0.58 ± 0.06*# |
| Blood triglyceride, mg/dl | 122.8 ± 15 | 151 ± 19 |
| Leptin, ng/ml | 3.76 ± 1.0 | 1.5 ± 0.33# |
| Acrp30, mg/ml | 20.9 ± 2.2 | 3.9 ± 0.72# |
| Muscular TG, μmol/g of tissue | 5.7 ± 2.0 | 7.6 ± 3.1 |
| Liver TG, μmol/g of tissue | 6.3 ± 2.0 | 11.7 ± 4.2# |
Data represent the mean ± SEM (n = 8). Blood was obtained from the Con and FKOγ mice before and during clamping study. *, P < 0.05, basal vs. clamping; #, P < 0.05, Con vs. FKOγ.