Table 1.

Molecules which have been shown to affect homing behavior of MSCs in preclinical model systems

Study [Ref]	Receptor	Result
Sackstein [12]	CD44/HCAM on hMSCs	fucosylation and sulfation before transplant restores ability of MSCs to home to bone marrow/bone
Herrera [49]	CD44 on mMSCs	improved recovery from acute renal failure only with CD44+ MSCs
Riister et al. [11]	yet unknown, fucosylated and sialylated P-selectin ligand on MSCs and endothelial P-selectin	rolling on endothelial cells under shear stress requires P-selectin in vitro and in vivo
Segers et al. [15]	VCAM-1 on cardiac microvascular endothelial cells	transmigration across endothelial cells in myocardial ischemia depends on flow rate and functional VCAM-1
Shi et al. [19]	CXCR4 upregulation by cytokine pre-treatment	increased engraftment of co-transplanted hHSCs
Hung [50]	hypoxia increases CXCR4 and CX3CR1 expression	increased MSC transmigration to chemokines, and increased engraftment in chick embryo assay