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. 2011 Apr 13;6(4):e18476. doi: 10.1371/journal.pone.0018476

Table 1. The physicochemical and biochemical properties of the 20 amino acids.

Amino Acid Polarity Secondary structure Molecular volume Codon diversity Electrostatic charge
A −0.591 −1.302 −0.733 1.57 −0.146
C −1.343 0.465 −0.862 −1.02 −0.255
D 1.05 0.302 −3.656 −0.259 −3.242
E 1.357 −1.453 1.477 0.113 −0.837
F −1.006 −0.59 1.891 −0.397 0.412
G −0.384 1.652 1.33 1.045 2.064
H 0.336 −0.417 −1.673 −1.474 −0.078
I −1.239 −0.547 2.131 0.393 0.816
K 1.831 −0.561 0.533 −0.277 1.648
L −1.019 −0.987 −1.505 1.266 −0.912
M −0.663 −1.524 2.219 −1.005 1.212
N 0.945 0.828 1.299 −0.169 0.933
P 0.189 2.081 −1.628 0.421 −1.392
Q 0.931 −0.179 −3.005 −0.503 −1.853
R 1.538 −0.055 1.502 0.44 2.897
S −0.228 1.399 −4.76 0.67 −2.647
T −0.032 0.326 2.213 0.908 1.313
V −1.337 −0.279 −0.544 1.242 −1.262
W −0.595 0.009 0.672 −2.128 −0.184
Y 0.26 0.83 3.097 −0.838 1.512

Listed below are the scores of the physicochemical and biochemical properties of the 20 amino acids, each of which can be coded by a 5-dimensional vector.