Table 2. Effect of MMR genes on recombination with galK point and insertion mutations.
Gal+ recombinants per 108 viable cells
|
||||
---|---|---|---|---|
galKam
|
galK<>cat-sacB
|
|||
MMR | 100 | 101 | 100 | 101 |
Allele* | ||||
mut+ | 4.7 × 105 | 2.4 × 104 | 1.2 × 105 | 4.0 × 103 |
ΔmutH | 2.1 × 107 | 5.8 × 105 | 5.2 × 104 | 1.7 × 103 |
ΔmutL | 2.2 × 107 | 7.5 × 105 | 1.0 × 105 | 9.0 × 102 |
ΔmutS | 3.6 × 107 | 1.5 × 106 | 1.4 × 105 | 3.3 × 103 |
ΔuvrD | 2.7 × 107 | 1.6 × 106 | † | † |
Δdam | 2.7 × 106 | 2.6 × 105 | 2.3 × 105 | 2.5 × 103 |
Spontaneous reversion to a Gal+ phenotype occurs at a frequency of ≈1 per 108 cells of strain HME6 mut+ and 24 per 108 cells of strain HME6 mutS.
Strain has not been made.