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. 2011 Apr 13;6(4):e18697. doi: 10.1371/journal.pone.0018697

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Kalogiannis et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Behavioral arrests in individual DKO mice. Left scale shows the total number of behavioral arrests in the three hour recording period by mouse (bars). Right scale shows the average duration of all recorded behavioral arrests (s; filled symbol) with the shortest and longest bouts indicated by the whiskers. (B) Mean (±SEM) total time per animal spent in behavioral arrest per 30 min bin shows that time spent in arrests increased substantially after the lights went out. (C) Total time per session for each mouse was variable (open symbols) but the mean (±SEM) time per mouse was stable across sessions (filled symbols). (D) Distribution of DKO behaviors prior to (1) and after (2) behavioral arrests.