Fig. 3.
Effect of wild-type and H67D Hfe alleles on hepatic iron content. Non-heme iron concentrations were determined in liver specimens from female (A) and male (B) wild-type mice (+/+), mice carrying a single wild-type Hfe allele (+/-), mice carrying a single H67D Hfe allele (H67D/-), and Hfe knock-out mice (-/-). Numbers in parentheses represent number of mice analyzed. Bars represent mean ± SEM. *, P < 0.05 compared with wild-type mice of same sex by ANOVA followed by Dunnett's posttest analyses.