Table 2.
Regression Parameters From the Hierarchical Linear Model Predicting Expected Smoking at Each Time Point
| Region | Overall intercept |
Slope of prior cravings |
Moderation of craving slope by brain activation |
|---|---|---|---|
| Target regions | |||
| Right IFG | 0.51 (5.35) | 0.24 (0.20) | −0.29* (0.12) |
| Left IFG | 0.51 (4.64) | 0.18 (0.15) | −0.23** (0.05) |
| Right pre-SMA | 0.50 (5.60) | 0.19 (0.18) | −0.20* (0.09) |
| Left pre-SMA | 0.50 (5.45) | 0.26* (0.12) | −0.23* (0.11) |
| Right basal ganglia | 0.54 (4.96) | 0.31* (0.14) | −0.27* (0.12) |
| Left basal ganglia | 0.52 (4.99) | 0.25* (0.12) | −0.32** (0.12) |
| Control regions | |||
| Right amygdala | 0.51 (5.22) | 0.24* (0.11) | 0.22* (0.09) |
| Left amygdala | 0.50 (5.89) | 0.16 (0.17) | 0.03 (0.07) |
| Right precuneus | 0.49 (5.82) | 0.19 (0.20) | 0.11 (0.08) |
| Left precuneus | 0.50 (6.06) | 0.19 (0.20) | 0.11 (0.08) |
Note: All parameters are reported in natural log units. Standard errors are given in parentheses. All models controlled for the linear decline in smoking across days, the negative quadratic pattern within days, and baseline nicotine dependence. IFG = inferior frontal gyrus; pre-SMA = pre-supplementary motor area.
p < .05.
p < .01.