Fig. 3.

Ring-stage parasites of both W2 and HB3 strains of Plasmodium falciparum were incubated with sub-lethal concentrations of all compounds (1.0 μM for RWJ68198 and 7.4 μM for all other compounds) and were grown under standard conditions of in vitro culture for 72 h. Thin blood smears were stained with 1% Giemsa stain and examined by phase-contrast microscopy at 24, 48, and 72 h, with representative images at 24 h being shown. Arrows have been placed at the periphery of representative aberrant trophozoites. Scale bar: 5 μm.