Table 3.
Free fatty acid changes
| Free fatty acid | Baseline | SD | Mean change omega-3 | SD | Mean change Placebo | SD | p-value |
|---|---|---|---|---|---|---|---|
| 14:0 | 1.27 | 0.8 | −0.10 | 0.8 | −0.18 | 0.8 | 0.82 |
| 15:0 | 0.23 | 0.1 | 0.01 | 0.1 | −0.03 | 0.1 | 0.02 |
| 16:0 | 20.64 | 2.6 | −1.20 | 2.4 | 0.08 | 2.2 | 0.22 |
| 18:0 | 8.07 | 0.7 | 0.15 | 0.6 | −0.17 | 0.6 | 0.22 |
| 20:0 | 0.18 | 0.0 | 0.02 | 0.0 | −0.02 | 0.1 | 0.10 |
| 22:0 | 0.41 | 0.2 | 0.06 | 0.1 | −0.10 | 0.2 | 0.02 |
| 24:0 | 0.37 | 0.1 | 0.06 | 0.1 | −0.09 | 0.1 | 0.01 |
| 14:1n5 | 0.09 | 0.1 | −0.03 | 0.1 | 0.00 | 0.1 | 0.45 |
| 16:1n7 | 1.29 | 0.7 | −0.37 | 0.8 | 0.03 | 0.5 | 0.22 |
| 18:1n7 | 1.19 | 0.2 | −0.05 | 0.1 | 0.07 | 0.2 | 0.20 |
| 18:1n9 | 18.90 | 3.6 | −2.43 | 4.6 | 1.44 | 1.9 | 0.01 |
| 20:1n9 | 0.17 | 0.1 | −0.03 | 0.1 | 0.00 | 0.1 | 0.32 |
| 20:3n9 | 0.09 | 0.0 | −0.02 | 0.0 | −0.01 | 0.0 | 0.42 |
| 22:1n9 | 0.03 | 0.0 | 0.00 | 0.0 | 0.00 | 0.0 | 0.35 |
| 24:1n9 | 0.36 | 0.1 | 0.06 | 0.1 | −0.02 | 0.1 | 0.15 |
| 18:2n6 | 33.72 | 4.8 | 2.04 | 5.5 | −0.66 | 4.4 | 0.15 |
| 18:3n6 | 0.57 | 0.3 | −0.15 | 0.4 | −0.06 | 0.3 | 0.64 |
| 20:2n6 | 0.32 | 0.1 | −0.03 | 0.1 | −0.03 | 0.1 | 0.56 |
| 20:3n6 | 1.54 | 0.4 | −0.30 | 0.6 | −0.04 | 0.3 | 0.30 |
| 20:4n6 | 6.30 | 1.5 | −0.28 | 1.5 | −0.10 | 0.9 | 0.38 |
| 22:2n6 | 0.01 | 0.0 | 0.00 | 0.0 | 0.00 | 0.0 | 0.49 |
| 22:4n6 | 0.25 | 0.1 | −0.06 | 0.1 | 0.00 | 0.0 | 0.03 |
| 22:5n6 | 0.22 | 0.1 | −0.08 | 0.1 | −0.01 | 0.0 | 0.01 |
| 18:3n3 | 0.78 | 0.4 | −0.02 | 0.3 | −0.02 | 0.3 | 0.95 |
| 18:4n3 | 0.04 | 0.0 | −0.01 | 0.0 | −0.01 | 0.0 | 0.81 |
| 20:4n3 | 0.07 | 0.0 | −0.01 | 0.0 | −0.02 | 0.0 | 0.82 |
| 20:5n3 (EPA) | 0.43 | 0.6 | 0.99 | 1.3 | −0.04 | 0.1 | 0.03 |
| 22:5n3 | 0.43 | 0.1 | 0.23 | 0.2 | −0.01 | 0.1 | 0.003 |
| 22:6n3 (DHA) | 1.34 | 0.8 | 1.36 | 1.4 | −0.01 | 0.2 | 0.02 |
| dm16:0 | 0.35 | 0.1 | 0.07 | 0.1 | −0.01 | 0.0 | 0.18 |
| dm18:0 | 0.23 | 0.1 | 0.08 | 0.1 | 0.00 | 0.1 | 0.10 |
| dm18:1n7 | 0.02 | 0.0 | 0.01 | 0.0 | 0.00 | 0.0 | 0.45 |
| dm18:1n9 | 0.11 | 0.0 | 0.00 | 0.1 | 0.01 | 0.0 | 0.95 |
| % Saturated | 31.75 | 3.3 | −0.84 | 3.0 | −0.51 | 2.8 | 0.60 |
| % Monounsaturated | 22.15 | 4.0 | −2.83 | 5.0 | 1.5 | 2.3 | 0.007 |
| % Polyunsaturated | 46.09 | 5.4 | 3.67 | 6.6 | −1.01 | 3.7 | 0.04 |
| % Omega-3 | 3.08 | 1.4 | 2.54 | 2.8 | −0.10 | 0.3 | 0.01 |
| % Omega-6 | 42.92 | 5.2 | 1.15 | 5.9 | −0.90 | 3.7 | 0.30 |
| % Omega-7 | 2.47 | 0.7 | −0.42 | 0.9 | 0.10 | 0.6 | 0.15 |
| % Omega-9 | 19.55 | 3.6 | −2.42 | 4.5 | 1.41 | 2.0 | 0.01 |
| % Dimethyl | 0.70 | 0.2 | 0.15 | 0.3 | 0.0 | 0.1 | 0.09 |
Fatty acids are described by their lipid number, which takes the form C:D, where C is the number of carbon atoms in the fatty acid and D is the number of double bonds in the fatty acid. All units are expressed as moles of fatty acid as a percentage of total moles fatty acid in the lipid class
dm dimethyl, EPA eicosapentanoic acid, DHA docosahexanoic acid