. 2010 Dec 8;67(5):493–506. doi: 10.1007/s00228-010-0948-5

Table 3.

Uncorrected serum concentrations (nM) of oxycodone, noroxycodone, oxymorphone, noroxymorphone and dose-corrected (nM × 100 mg 24 h⁻¹/dose 24 h⁻¹) serum concentrations, and ratios noroxycodone/oxycodone and oxymorphone/oxycodone given as median, 25th and 75th percentiles, minimum to maximum values, mean and 95% CI for mean for the hospitalised patients

Serum concentrations	Median	25th percentile	75th percentile	Minimum to maximum	Mean	95% CI
Serum concentrations	Median	25th percentile	75th percentile	Minimum to maximum	Mean	Low	High
Oxycodone^a	97	43	201	0–1,890	161	139	183
Oxycodone^b	144	90	225	0–1,294	186	170	203
Noroxycodone^a	101	44	211	0–3,571	209	174	245
Noroxycodone^b	161	103	261	0–3,032	212	188	235
Oxymorphone^a	1.5	0.7	3.2	0–25	2.6	2.3	3.0
Oxymorphone^b	2.2	1.2	4.2	0–34	3.4	3.0	3.8
Noroxymorphone^a	17	8	39	0–509	30	26	34
Noroxymorphone^b	29	18	44	0–360	34	31	38
Ratio noroxycodone/oxycodone^a	1.1	0.7	1.9	0.1–24.4	1.6	1.4	1.8
Ratio oxymorphone/oxycodone^a	0.02	0.01	0.03	0.00032–0.21	0.02	0.02	0.02

^aUncorrected serum concentrations

^bDose-corrected serum concentrations