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Biomarkers of Fatigue in Sickle Cell Disease
| Variable | Biomarker |
|---|---|
| Hypoxemia | |
| Deoxygenation | Partial pressure of oxygen (PaO2) -Arterial blood gas |
| Arterial oxygen saturation (SaO2) -Pulse oximetry |
|
| Anemia and hyperviscosity | Hemoglobin |
| Hematocrit | |
| Inflammation | IL-1 |
| IL-6 | |
| TNF-α | |
| Stress | Cortisol |
| Heart rate variability |
