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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Neurosci Biobehav Rev. 2010 Nov 30;35(5):1125–1143. doi: 10.1016/j.neubiorev.2010.11.005

Figure 3. Examples of Activations in clinical models of pain.

Figure 3

A: Visceral Pain: Activation in the thalamus in response to abdominal stimulation in a model of visceral pain ((Westlund et al., 2009); with permission, Neuroimage). Note the increase in the lateral and dorsal thalamus suggesting increased activation in lateral and medial pain pathways.

B: Neuropathic Pain: Activation in response to trunk stimulation in a rat model of spinal cord injury. Panel A shows activation in response to the stimuli in SI (arrow) in normal animals that is increased in the injured animal ((Endo et al., 2008a); with Permission, IASP Press).

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