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. Author manuscript; available in PMC: 2012 Mar 10.

Published in final edited form as: J Med Chem. 2011 Feb 7;54(5):1490–1510. doi: 10.1021/jm101535e

Table 1.

EC₅₀ values of hNod1 agonistic activities of analogues

Cmpd	Structure	EC₅₀ (nM)
16		0.027
18		0.55
20		0.58
22		0.023
26		26: 0.20
28		28: 0.12
27		0.0015
30		1.31
32		0.622
35		0.066
37		0.826
41		0.134
43		0.238
45		0.069
48		0.181
50		0.145
53		0.504
56		0.39
67		>100
69		>100
71		1.73
73		>100
75		0.37
77		0.57
79		0.96