FIGURE 1.

Study design. Upper panel: for the acute pilot study, participants (n = 15) received cranberry juice and vascular testing was repeated 2 and 4 h after juice consumption. Lower panel: for the chronic crossover study, participants were randomly assigned to consume cranberry juice first (upper row; n = 24) or placebo first (lower row; n = 23) and consumed the assigned beverage for 4 wk. After a 2-wk rest period, they then crossed over to the alternate beverage. Two subjects withdrew while consuming cranberry juice because of dyspepsia, and one subject withdrew because of scheduling problems while consuming placebo. A total of 44 subjects completed the study.