TABLE 3.
Chronic effects of cranberry juice on vascular function1
| Vascular function variable | Beforejuice | Afterjuice | Before placebo | After placebo | P2 |
| Systolic blood pressure (mm Hg) | 131 ± 16 | 133 ± 18 | 133 ± 17 | 135 ± 18 | 0.44 |
| Diastolic blood pressure (mm Hg) | 72 ± 9 | 73 ± 9 | 74 ± 8 | 74 ± 9 | 0.94 |
| Flow-mediated dilation (%) | 6.3 ± 4.4 | 6.7 ± 4.4 | 6.5 ± 4.0 | 6.6 ± 3.9 | 0.69 |
| Baseline diameter (mm) | 4.58 ± 0.70 | 4.55 ± 0.68 | 4.53 ± 0.70 | 4.53 ± 0.65 | 0.64 |
| Dilation to nitroglycerin (%) | 8.7 ± 5.0 | 9.5 ± 4.9 | 11 ± 4.8 | 10 ± 5.2 | 0.21 |
| Baseline flow (mL/min) | 176 ± 74 | 195 ± 82 | 187 ± 65 | 184 ± 70 | 0.09 |
| Hyperemic flow (mL/min) | 1106 ± 388 | 1198 ± 377 | 1086 ± 350 | 1146 ± 380 | 0.56 |
| lnPAT ratio | 0.40 ± 0.36 | 0.36 ± 0.34 | 0.29 ± 0.29 | 0.33 ± 0.30 | 0.33 |
| Cartoid-radial PWV (m/s) | 8.2 ± 1.9 | 7.9 ± 1.6 | 8.1 ± 1.3 | 7.9 ± 1.4 | 0.47 |
| Cartoid-femoral PWV (m/s) | 8.3 ± 2.3 | 7.8 ± 2.2 | 8.0 ± 2.0 | 8.4 ± 2.8 | 0.003 |
1
All values are means ± SDs; n = 44. PAT, pulse amplitude tonometry measured in the finger; PWV, pulse wave velocity measured by applanation tonometry.
2
P for treatment by follow-up interaction as determined by using a general linear model for correlated data with PROC MIXED, an unstructured covariance matrix, and standard residual maximum likelihood estimation in SAS (SAS Institute Inc, Cary, NC).