TABLE 1.
Characteristics of the study population1
| MI (n = 24) | NoMI-PI (n = 70) | PS (n = 9) | P | |
| Sex [n (%)] | 0.202 | |||
| M | 9 (38) | 39 (56) | 6 (67) | — |
| F | 15 (62) | 31 (44) | 3 (33) | — |
| Birth weight (g) | 3120 ± 5323 | 3310 ± 466 | 3413 ± 430 | 0.174 |
| Birth weight z score | −0.57 ± 1.08 | −0.27 ± 0.89 | −0.12 ± 0.79 | 0.314 |
| Median age at diagnosis (wk) | 1.1 | 1.7 | 2.6 | 0.155 |
| Genotype [n (%)] | <0.0016 | |||
| F508del/F508del | 14 (58) | 30 (43) | 0 | — |
| F508del/other | 9 (38) | 36 (52) | 8 (89) | — |
| Other/other | 1 (4) | 4 (6) | 1 (11) | — |
| Breast or formula feeding [n (%)] | 0.0456 | |||
| ExBF <1 mo | 10 (42) | 16 (23) | 2 (22) | — |
| ExBF = 1 mo | 1 (4) | 8 (11) | 2 (22) | — |
| ExBF ≥2 mo | 2 (8) | 10 (14) | 2 (22) | — |
| ExFM20 | 2 (8) | 22 (31) | 3 (33) | — |
| ExFM22+ | 9 (38) | 14 (20) | 0 | — |
1
MI, meconium ileus; NoMI-PI, no MI but pancreatic insufficient; PS, pancreatic sufficient; ExBF, exclusive breastfeeding; ExBF = 1 mo, ExBF for 1–1.9 mo; ExFM20, exclusively fed formula containing standard caloric density of 0.67 kcal/mL (equivalent to 20 kcal/oz); ExFM22+, exclusively formula-fed and received high caloric density formula [≥0.74 kcal/mL (≥22 kcal/oz)] for some duration during infancy.
2
Calculated by using the chi-square test.
3
Mean ± SD (all such values).
4
Calculated by using one-factor ANOVA.
5
Calculated by using the Median test.
6
Calculated by using Fisher's exact test.