Table 1. Age-dependent susceptibility to EV1-induced disease.
Genotype | Age | n | Paralyzed | Wasting |
---|---|---|---|---|
α2/β1 | 24–48 h | 72 | 46/72 | 12/72 |
α2 | 24–48 h | 52 | 12/52 | 14/52 |
–/– | 24–48 h | 28 | 0/28 | 0/28 |
α2/β1 | 3–4 wk | 81 | 0/81 | 26/81 |
α2 | 3–4 wk | 107 | 0/107 | 41/107 |
–/– | 3–4 wk | 42 | 0/42 | 0/42 |
Newborn and adolescent mice were inoculated i.c. with 109 PFU of EV1. n, number of mice infected.