TABLE II.

Magnitude of primary analysis signal increases following fine-mapping for a disease allele frequency of 0.2

Genetic model		Single SNP analysis				Five-SNP haplotype sliding window analysis
		Size of increase (order of magnitude)				Size of increase (order of magnitude)
GRRhom	GRRhet	Any	≥1	≥2	≥3	Any	≥1	≥2	≥3
1.0	1.0	306	16	1	0	369	40	1	0
1.5	1.5	612	136	57	22	767	237	52	12
1.5	1.0	370	13	2	0	443	51	2	0
1.5	1.25	522	54	8	6	641	115	17	0
2.0	2.0	705	392	269	211	850	493	265	157
2.0	1.0	449	26	4	0	518	67	3	1
2.0	1.5	648	204	100	51	786	303	95	35
3.0	3.0	702	491	411	347	891	661	464	356
3.0	1.0	495	46	5	0	613	113	10	1
3.0	2.0	680	397	325	266	850	520	288	192